The Klonopin Klub#2

[[or...]]

I just think the simplest, but most accurate is the way to go, for whoever is trying to put their plan together.  I'd like to see something like that, but when I person gets down into their micro type tapers, is where I see it getting touch and go as for good results    Ok, too negative a thought for now, I'm far from jumping off the med   I'll worry later, LOL!!

[[or...]]

My day has turned out so good, thanks to you SS and the others on BB I got a lot done including grocery shopping and my recycling takin to our dumpster for it. 

 

I really think just being able to vent, cry, is healing somehow   I have a bone-density scan at 2:20 so hope it turns out good, never had one before and I think I'm ok in that area, but a test is probably smart at 70, who knows for sure.  I'll do it, once!!

[[...]]

Hi OL,

 

I'm glad to hear your day has been going well. I hope your bone scan came out great!

 

I was wondering, do you take your clonazepam once a day or multiple times a day.

 

I have to say I agree with SS about holding. I did a six month hold at one point and it made a world of difference moving forward.

[[or...]]

Hi OL,

 

I'm glad to hear your day has been going well. I hope your bone scan came out great!

 

I was wondering, do you take your clonazepam once a day or multiple times a day.

 

I have to say I agree with SS about holding. I did a six month hold at one point and it made a world of difference moving forward.

[/quote

Yes just One a day 👍😁

[[Pa...]]

Please call a pharmacist to learn if a particular medication is dissolved in water or alcohol.  I checked with mine and did learn my brand of Clonazapam does not dissolve in water.  It looks dissolved but it is not.  I used 1 ml of Titos vodka to dissolve my tab and then added enough water to make my titration liquid.  Things went much more smoothly after I did this.

 

Klonkar

 

I’m delighted your do-it-youself (DIY) clonazepam liquid worked for you.  The pharmacist you called was correct - clonazepam has very low solubility in water. However, please be aware that …

 

According to the experimental solubility study cited below, 1mL of 40% vodka would not be sufficient to dissolve 1mg of pure clonazepam powder (much less 1mg of clonazepam powder mixed with other ingredients and pressed into tablets).  Moreover, even if some of the clonazepam in your tablet did actually dissolve, adding more water to your tablet/vodka slurry decreased the concentration of alcohol in the liquid. This raises the possibility of precipitation - i.e. clonazepam that did go into solution when you added the vodka may have precipitated back out of solution when you added more water because the concentration of alcohol in your DIY liquid decreased.

 

Citation:

Ali Shayanfar, Mohammad A. A. Fakhree, William E. Acree , Jr. and Abolghasem Jouyban. Solubility of Lamotrigine, Diazepam, and Clonazepam in Ethanol + Water Mixtures at 298.15 K, J. Chem. Eng. Data, 2009, 54 (3), pp 1107–1109, December 22, 2008.

 

Yes  -- I don't have a citation here--  but builder oft quoted that 2ml of alcohol were required for every 1mg of benzo.  yes he said benzo, did not differentiate.  I make sure to dissolve things for along time to insure a solution - and I mix the solution carefully before ingesting. 

 

Just so you know, builder had no personal experience with making/using the do-it-yourself liquids he promoted to others, he used the FDA-approved, commercially manufactured oral diazepam solution to taper. He also failed to fully inform members about the risks/pitfalls of his approach to daily microtapering using do it yourself liquids which caused a good number of members to crash and burn.

 

I understand you’ve found something that works for you but it doesn’t work for everyone and no matter how the liquid looks after you add the vodka and water, it is not a solution, its a suspension and must be agitated before ingestion.

 

[[Co...]]

Oh wow, important to point out, Pamster! I had no idea reading the old posts he didn't even use it himself.

[[Su...]]

I could not do a liquid taper. I tried two different formulations, and neither worked for me. We're all very different.

Yes we are -- and for me I continue to need to do the majority of my dose in pill form and then the smallest amount in liquid that I can for tapering.  I also make my own juice.

When I went to all liquid it was a gong show.

[[Su...]]

Please call a pharmacist to learn if a particular medication is dissolved in water or alcohol.  I checked with mine and did learn my brand of Clonazapam does not dissolve in water.  It looks dissolved but it is not.  I used 1 ml of Titos vodka to dissolve my tab and then added enough water to make my titration liquid.  Things went much more smoothly after I did this.

 

Klonkar

 

I’m delighted your do-it-youself (DIY) clonazepam liquid worked for you.  The pharmacist you called was correct - clonazepam has very low solubility in water. However, please be aware that …

 

According to the experimental solubility study cited below, 1mL of 40% vodka would not be sufficient to dissolve 1mg of pure clonazepam powder (much less 1mg of clonazepam powder mixed with other ingredients and pressed into tablets).  Moreover, even if some of the clonazepam in your tablet did actually dissolve, adding more water to your tablet/vodka slurry decreased the concentration of alcohol in the liquid. This raises the possibility of precipitation - i.e. clonazepam that did go into solution when you added the vodka may have precipitated back out of solution when you added more water because the concentration of alcohol in your DIY liquid decreased.

 

Citation:

Ali Shayanfar, Mohammad A. A. Fakhree, William E. Acree , Jr. and Abolghasem Jouyban. Solubility of Lamotrigine, Diazepam, and Clonazepam in Ethanol + Water Mixtures at 298.15 K, J. Chem. Eng. Data, 2009, 54 (3), pp 1107–1109, December 22, 2008.

 

Yes  -- I don't have a citation here--  but builder oft quoted that 2ml of alcohol were required for every 1mg of benzo.  yes he said benzo, did not differentiate.  I make sure to dissolve things for along time to insure a solution - and I mix the solution carefully before ingesting. 

 

Just so you know, builder had no personal experience with making/using the do-it-yourself liquids he promoted to others, he used the FDA-approved, commercially manufactured oral diazepam solution to taper. He also failed to fully inform members about the risks/pitfalls of his approach to daily microtapering using do it yourself liquids which caused a good number of members to crash and burn.

 

I understand you’ve found something that works for you but it doesn’t work for everyone and no matter how the liquid looks after you add the vodka and water, it is not a solution, its a suspension and must be agitated before ingestion.

 

Interesting Pamster.

I didn't know that builder didn't use his own formula.

  I do think it forms a solution with the dissolved benzo and it has worked for me, although who knows maybe if I'd used a formulated solution I could have gone faster?

I know that there is a trend right now on the boards for water titration where you throw part of your dose away and that actually scares me a bit.  The throwing away seems unnecessary when some can't get enough meds to be that wasteful, and there is lots of documentation that benzos don't dissolve in water (yes I know Versed -- primarily used before surgery, Dalmane-- no longer available in the US, and librium very seldom used by anyone are water soluble)

I'm just trying to get other options out there.

I see the way the winds blow here though and I'll keep that in mind.

[[or...]]

I gotta tell you gals/guys, whoever is reading this, that I am getting nervous about liquid tapering.  Right now I am looking "heavily" into dry taporing even small doses.  My biggest issue is I have a scale for jewelry but evidently I can use it for pills/powder, but I don't know what the "calibration" is for.  Never done this before in my life so if anyone can help me by pointing out any info on calibration, or explaining it to me, I would so appreciate it

 

I have one video I'm watching now from a post done by Pamster, but nothing on why the calibration has to be done.  I simply can't figure it out.  I always just stand on my scale in the bathroom, never had to worry about a calibration, whatever that is 

 

My benzo brain finally gave me a break, I found the answer by just asking google why do I have to calibrate a scale, lol, duh!!

 

"Calibration is necessary because its accuracy might diminish when you routinely use the scales and demonstrate false readings. Calibrate your industrial weighing scales regularly to prevent the scale's accuracy from degrading".

[[Su...]]

I gotta tell you gals/guys, whoever is reading this, that I am getting nervous about liquid tapering.  Right now I am looking "heavily" into dry taporing even small doses.  My biggest issue is I have a scale for jewelry but evidently I can use it for pills/powder, but I don't know what the "calibration" is for.  Never done this before in my life so if anyone can help me by pointing out any info on calibration, or explaining it to me, I would so appreciate it

 

I have one video I'm watching now from a post done by Pamster, but nothing on why the calibration has to be done.  I simply can't figure it out.  I always just stand on my scale in the bathroom, never had to worry about a calibration, whatever that is 

 

My benzo brain finally gave me a break, I found the answer by just asking google why do I have to calibrate a scale, lol, duh!!

 

"Calibration is necessary because its accuracy might diminish when you routinely use the scales and demonstrate false readings. Calibrate your industrial weighing scales regularly to prevent the scale's accuracy from degrading".

 

I sure understand your hesitancy with all the stuff that's being thrown around about liquid. 

Mostly it's important that you find a way that is accurate and something you can do easily

 

[[he...]]

Just so you know, builder had no personal experience with making/using the do-it-yourself liquids he promoted to others, he used the FDA-approved, commercially manufactured oral diazepam solution to taper. He also failed to fully inform members about the risks/pitfalls of his approach to daily microtapering using do it yourself liquids which caused a good number of members to crash and burn.

 

I understand you’ve found something that works for you but it doesn’t work for everyone and no matter how the liquid looks after you add the vodka and water, it is not a solution, its a suspension and must be agitated before ingestion.

 

Yes, all his responses on those old threads where he asserted with absolute certainty that everyone can water taper and do great, symptoms will be reduced, and tolerance withdrawal (or whatever you want to call the phenomenon) doesn't exist exasperate me. He refused to acknowledge that some people cannot use a liquid, some people will have tough symptoms as they taper, and some people started having tough symptoms before tapering while taking their med as prescribed.

[[Co...]]

Yeah I had symptoms after day 5, but I think it's more that that itself doesn't matter if you taper safely. Only my baseline is horrible due to the large cut in the beginning and the cortisone withdrawal.

[[or...]]

Can't agree more SS.  I've got time since I am holding at the .75 for now  but time seems to fly, truly, and I do want my basic plan layed out so I'll just keep doing a little bit of research each day until I feel comfy (as possible) on my "how to" 

[[Su...]]

Just so you know, builder had no personal experience with making/using the do-it-yourself liquids he promoted to others, he used the FDA-approved, commercially manufactured oral diazepam solution to taper. He also failed to fully inform members about the risks/pitfalls of his approach to daily microtapering using do it yourself liquids which caused a good number of members to crash and burn.

 

I understand you’ve found something that works for you but it doesn’t work for everyone and no matter how the liquid looks after you add the vodka and water, it is not a solution, its a suspension and must be agitated before ingestion.

 

Yes, all his responses on those old threads where he asserted with absolute certainty that everyone can water taper and do great, symptoms will be reduced, and tolerance withdrawal (or whatever you want to call the phenomenon) doesn't exist exasperate me. He refused to acknowledge that some people cannot use a liquid, some people will have tough symptoms as they taper, and some people started having tough symptoms before tapering while taking their med as prescribed.

 

Yes everyone is a mixed bag aren't they?  But I tend to not throw out the baby with the bath water.  I've used his method of creating a home-brew for years and I am extremely kindled something he said didn't exist  .

 

In this time of tapering I have weirdly or   NEVER had the "waves and windows" phenomenon that folks speak of.  If I have a rough patch I can see exactly where I cut too much and I can adjust my liquid to insure that doesn't happen again.

 

I still can't understand how one can get precision cutting pills that are such different weights.  Yes!  I've heard the theories!  No please don't tell me again -- (when there's a .07mg difference in weight and I'm cutting less than .01..... )

 

OK OK I said I'd shut up 

 

[[Su...]]

Can't agree more SS.  I've got time since I am holding at the .75 for now  but time seems to fly, truly, and I do want my basic plan layed out so I'll just keep doing a little bit of research each day until I feel comfy (as possible) on my "how to" 

 

:thumbsup:

[[or...]]

Just so you know, builder had no personal experience with making/using the do-it-yourself liquids he promoted to others, he used the FDA-approved, commercially manufactured oral diazepam solution to taper. He also failed to fully inform members about the risks/pitfalls of his approach to daily microtapering using do it yourself liquids which caused a good number of members to crash and burn.

 

I understand you’ve found something that works for you but it doesn’t work for everyone and no matter how the liquid looks after you add the vodka and water, it is not a solution, its a suspension and must be agitated before ingestion.

 

Yes, all his responses on those old threads where he asserted with absolute certainty that everyone can water taper and do great, symptoms will be reduced, and tolerance withdrawal (or whatever you want to call the phenomenon) doesn't exist exasperate me. He refused to acknowledge that some people cannot use a liquid, some people will have tough symptoms as they taper, and some people started having tough symptoms before tapering while taking their med as prescribed.

 

Yes everyone is a mixed bag aren't they?  But I tend to not throw out the baby with the bath water.  I've used his method of creating a home-brew for years and I am extremely kindled something he said didn't exist  .

 

In this time of tapering I have weirdly or   NEVER had the "waves and windows" phenomenon that folks speak of.  If I have a rough patch I can see exactly where I cut too much and I can adjust my liquid to insure that doesn't happen again.

 

I still can't understand how one can get precision cutting pills that are such different weights.  Yes!  I've heard the theories!  No please don't tell me again -- (when there's a .07mg difference in weight and I'm cutting less than .01..... )

 

OK OK I said I'd shut up 

  LOL, well said, made me think again and my poor ole benzo brain I think, does need exercise and BB is the place to get it 

[[or...]]

Ok, this is really weird as I just weighed my 3/4 of a tablet I've been taking, never weighed it before, calibrated my little scale and got .151 of a gram?? I don't see  a choice to click on "mode" button to get mg or ml.  Is there a mathmatician in the group  Help!! 

 

I just want to get the hang of this jewelry scale but I think it might not be working right, ya think??

[[Li...]]

I do think it forms a solution with the dissolved benzo and it has worked for me ….

 

Once again, I am delighted your do-it-yourself liquid has worked for you.  However, am I correct that you are tapering diazepam, not clonazepam?  If so, I encourage you and other readers to keep in mind that different benzodiazepines have different solubilities in different solvents.

 

Case in point …

 

Diazepam has a much higher solubility in alcohol than clonazepam.  So, the ‘recipe’ you are using may indeed dissolve at least some of the diazepam in your tablet.  However, please bear in mind that when you add additional water to your vodka/diazepam-tablet slurry, the concentration of alcohol in the liquid decreases (the pH may also change).  Consequently, it’s entirely possible that some of the diazepam will precipitate back out of solution.

 

The bottom line is we don’t know the properties of any of the do-it-yourself (DIY) liquids because they have not been professionally analyzed.  Consequently, as Pamster has indicated, we suggest that members regard DIY liquids as temporary suspensions with unknown pharmacokinetic properties and stability/shelf-life.

 

Although well-intentioned, the individuals who developed the ‘one-size-fits-all-benzos’ recipe you are using were laypeople — not analytical chemists, pharmaceutical scientists, or drug formulation specialists.  They relied on data from only one experimental solubility study (cited upthread) that has not been replicated by other researchers (indeed, at least one of the solubilities reported in the study is markedly different from other sources, thus raising a caution flag about the study results in general; another weakness of the study is that it did not include Xanax/alprazolam). 

 

These well-intentioned laypeople also did not follow basic principles of drug formulation development such as including a significant ‘buffer zone’ around how much drug one can realistically expect to stay dissolved in a liquid drug formulation. For example, if a drug molecule has an experimental solubility of 7mg in 100mL of solvent (or co-solvent system), my understanding is the general rule of thumb in pharma is to divide 7 by 3-5 (or even 10) to get a ‘working’ solubility closer to 1-2mg of drug per 100 mL.

[[Su...]]

I do think it forms a solution with the dissolved benzo and it has worked for me ….

 

Once again, I am delighted your do-it-yourself liquid has worked for you.  However, am I correct that you are tapering diazepam, not clonazepam?  If so, I encourage you and other readers to keep in mind that different benzodiazepines have different solubilities in different solvents.

 

Case in point …

 

Diazepam has a much higher solubility in alcohol than clonazepam.  So, the ‘recipe’ you are using may indeed dissolve at least some of the diazepam in your tablet.  However, please bear in mind that when you add additional water to your vodka/diazepam-tablet slurry, the concentration of alcohol in the liquid decreases (the pH may also change).  Consequently, it’s entirely possible that some of the diazepam will precipitate back out of solution.

 

The bottom line is we don’t know the properties of any of the do-it-yourself (DIY) liquids because they have not been professionally analyzed.  Consequently, as Pamster has indicated, we suggest that members regard DIY liquids as temporary suspensions with unknown pharmacokinetic properties and stability/shelf-life.

 

Although well-intentioned, the individuals who developed the ‘one-size-fits-all-benzos’ recipe you are using were laypeople — not analytical chemists, pharmaceutical scientists, or drug formulation specialists.  They relied on data from only one experimental solubility study (cited upthread) that has not been replicated by other researchers (indeed, at least one of the solubilities reported in the study is markedly different from other sources, thus raising a caution flag about the study results in general; another weakness of the study is that it did not include Xanax/alprazolam). 

 

These well-intentioned laypeople also did not follow basic principles of drug formulation development such as including a significant ‘buffer zone’ around how much drug one can realistically expect to stay dissolved in a liquid drug formulation. For example, if a drug molecule has an experimental solubility of 7mg in 100mL of solvent (or co-solvent system), my understanding is the general rule of thumb in pharma is to divide 7 by 3-5 (or even 10) to get a ‘working’ solubility closer to 1-2mg of drug per 100 mL.

 

All excellent points Libertas!

Now for the citations around the concentrations of medication in the dry cut pills?

And for the water titration of 300ml being accurate as it's being used frequently here?

 

Again I'm not trying to be argumentative here but there is so much information that is thrown around here -- I hope you jump on that as quickly as you jump on my claims. 

 

And it's funny and a character trait of mine for sure  that I'm much more comfortable making something myself than trusting a pharmacy.  I once asked a pharmacy to spit pills and they all came back in basically unusable pieces.

 

I am wanting us all to be safe and doing what is accurate with medications that for years the experts you cited said were not a problem -- actually continue to say are not a problem.  Do I trust authority?  nah not blindly for sure!

 

Not questioning your citations here, just pointing out that there is so much unknown in this process.

I'll stop promoting a home brew but will continue to promote liquid for a portion of the dose.

[[or...]]

Libertas, you seem a wise person to ask a question about Jewelry scale. My little jewelry scale has a gram option (no mg that I see), so I weigh my 3/4 of 1 mg tablet on the scale and get .151 of a gram.  I thought about taking 0.75 and .151 but got stuck. Of I subtract 0.75 from .151 I get .599 which is rounded to 0.60 mg.  Is that right?  If so, my dry cutting is off in saying I've been taking .75 mg of 1 mg.

 

Can you help me, I'm raising my hand, help!!

[[or...]]

I do think it forms a solution with the dissolved benzo and it has worked for me ….

 

Once again, I am delighted your do-it-yourself liquid has worked for you.  However, am I correct that you are tapering diazepam, not clonazepam?  If so, I encourage you and other readers to keep in mind that different benzodiazepines have different solubilities in different solvents.

 

Case in point …

 

Diazepam has a much higher solubility in alcohol than clonazepam.  So, the ‘recipe’ you are using may indeed dissolve at least some of the diazepam in your tablet.  However, please bear in mind that when you add additional water to your vodka/diazepam-tablet slurry, the concentration of alcohol in the liquid decreases (the pH may also change).  Consequently, it’s entirely possible that some of the diazepam will precipitate back out of solution.

 

The bottom line is we don’t know the properties of any of the do-it-yourself (DIY) liquids because they have not been professionally analyzed.  Consequently, as Pamster has indicated, we suggest that members regard DIY liquids as temporary suspensions with unknown pharmacokinetic properties and stability/shelf-life.

 

Although well-intentioned, the individuals who developed the ‘one-size-fits-all-benzos’ recipe you are using were laypeople — not analytical chemists, pharmaceutical scientists, or drug formulation specialists.  They relied on data from only one experimental solubility study (cited upthread) that has not been replicated by other researchers (indeed, at least one of the solubilities reported in the study is markedly different from other sources, thus raising a caution flag about the study results in general; another weakness of the study is that it did not include Xanax/alprazolam). 

 

These well-intentioned laypeople also did not follow basic principles of drug formulation development such as including a significant ‘buffer zone’ around how much drug one can realistically expect to stay dissolved in a liquid drug formulation. For example, if a drug molecule has an experimental solubility of 7mg in 100mL of solvent (or co-solvent system), my understanding is the general rule of thumb in pharma is to divide 7 by 3-5 (or even 10) to get a ‘working’ solubility closer to 1-2mg of drug per 100 mL.

 

All excellent points Libertas!

Now for the citations around the concentrations of medication in the dry cut pills?

And for the water titration of 300ml being accurate as it's being used frequently here?

 

Again I'm not trying to be argumentative here but there is so much information that is thrown around here -- I hope you jump on that as quickly as you jump on my claims. 

 

And it's funny and a character trait of mine for sure  that I'm much more comfortable making something myself than trusting a pharmacy.  I once asked a pharmacy to spit pills and they all came back in basically unusable pieces.

 

I am wanting us all to be safe and doing what is accurate with medications that for years the experts you cited said were not a problem -- actually continue to say are not a problem.  Do I trust authority?  nah not blindly for sure!

 

Not questioning your citations here, just pointing out that there is so much unknown in this process.

I'll stop promoting a home brew but will continue to promote liquid for a portion of the dose.

I'm thinking it's more about Math, and yes, figuring out myself on dosage, and how to be as accurate as possible.  Math is my biggest problem here  

 

I'm doing the learning as much as my benzo brain can retain/absorb and I may have to become a biochemist before it's all over, LOL! Even then, I'd still be that imperfect humanoid 

[[Su...]]

I do think it forms a solution with the dissolved benzo and it has worked for me ….

 

Once again, I am delighted your do-it-yourself liquid has worked for you.  However, am I correct that you are tapering diazepam, not clonazepam?  If so, I encourage you and other readers to keep in mind that different benzodiazepines have different solubilities in different solvents.

 

Case in point …

 

Diazepam has a much higher solubility in alcohol than clonazepam.  So, the ‘recipe’ you are using may indeed dissolve at least some of the diazepam in your tablet.  However, please bear in mind that when you add additional water to your vodka/diazepam-tablet slurry, the concentration of alcohol in the liquid decreases (the pH may also change).  Consequently, it’s entirely possible that some of the diazepam will precipitate back out of solution.

 

The bottom line is we don’t know the properties of any of the do-it-yourself (DIY) liquids because they have not been professionally analyzed.  Consequently, as Pamster has indicated, we suggest that members regard DIY liquids as temporary suspensions with unknown pharmacokinetic properties and stability/shelf-life.

 

Although well-intentioned, the individuals who developed the ‘one-size-fits-all-benzos’ recipe you are using were laypeople — not analytical chemists, pharmaceutical scientists, or drug formulation specialists.  They relied on data from only one experimental solubility study (cited upthread) that has not been replicated by other researchers (indeed, at least one of the solubilities reported in the study is markedly different from other sources, thus raising a caution flag about the study results in general; another weakness of the study is that it did not include Xanax/alprazolam). 

 

These well-intentioned laypeople also did not follow basic principles of drug formulation development such as including a significant ‘buffer zone’ around how much drug one can realistically expect to stay dissolved in a liquid drug formulation. For example, if a drug molecule has an experimental solubility of 7mg in 100mL of solvent (or co-solvent system), my understanding is the general rule of thumb in pharma is to divide 7 by 3-5 (or even 10) to get a ‘working’ solubility closer to 1-2mg of drug per 100 mL.

 

All excellent points Libertas!

Now for the citations around the concentrations of medication in the dry cut pills?

And for the water titration of 300ml being accurate as it's being used frequently here?

 

Again I'm not trying to be argumentative here but there is so much information that is thrown around here -- I hope you jump on that as quickly as you jump on my claims. 

 

And it's funny and a character trait of mine for sure  that I'm much more comfortable making something myself than trusting a pharmacy.  I once asked a pharmacy to spit pills and they all came back in basically unusable pieces.

 

I am wanting us all to be safe and doing what is accurate with medications that for years the experts you cited said were not a problem -- actually continue to say are not a problem.  Do I trust authority?  nah not blindly for sure!

 

Not questioning your citations here, just pointing out that there is so much unknown in this process.

I'll stop promoting a home brew but will continue to promote liquid for a portion of the dose.

I'm thinking it's more about Math, and yes, figuring out myself on dosage, and how to be as accurate as possible.  Math is my biggest problem here  

 

I'm doing the learning as much as my benzo brain can retain/absorb and I may have to become a biochemist before it's all over, LOL! Even then, I'd still be that imperfect humanoid 

 

The math is fairly simple -- really!  Once you are done holding, which you may do for a bit?  it's a basic formula  than you can get help with. 

 

[[or...]]

So will you show me how I weigh in at .151 in grams, and how that converts to, or compares to .75 of a mg if it's simple

 

I asked that of Libertas but not answer back yet.  I know, not everyone lives on this forum like I do 

[[Li...]]

 

All excellent points Libertas!

Now for the citations around the concentrations of medication in the dry cut pills?

And for the water titration of 300ml being accurate as it's being used frequently here?

 

 

You’ve lost me.  Where did I write anything about the concentration of drug in pills?  Where did I claim that the 300mL water titration technique is accurate?  Perhaps you are confusing me with another member?

 

… just pointing out that there is so much unknown in this process.

 

I'll stop promoting a home brew but will continue to promote liquid for a portion of the dose.

 

 

I agree wholeheartedly — there are more unknowns than knowns.  That’s why we all should be cautious about making claims we cannot substantiate with credible evidence/citation. 

 

No one is asking you to stop sharing the approach you are using or your personal experience. What I am suggesting is that you might want to include relevant information when you do so (e.g. you are making your DIY liquid using diazepam tablets; your approach may not apply to other benzodiazepines).

[[Su...]]

So will you show me how I weigh in at .151 in grams, and how that converts to, or compares to .75 of a mg if it's simple

 

I asked that of Libertas but not answer back yet.  I know, not everyone lives on this forum like I do 

 

Im going to let the folks who are doing a dry cut taper weigh in on that one!  I do know that the math is fairly simple, not trying to be patronizing here -- just reassuring??

VintageGuitar is a good guy for explaining.....