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Study, Mar./16: SSRI-induced weight changes


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The full title of the study from India is "Selective Serotonin Re-uptake Inhibitors (SSRIs) Induced Weight Changes: A Dose and Duration Dependent Study on Albino Rats".


From the abstract:


"RESULTS: All experimental group rats which received fluoxetine showed decrease of body weight. Rats which received high doses of fluoxetine could not tolerate the drug for more than two weeks and died due to excessive body weight loss, loose stools and muscle twitching."


"CONCLUSION: Present study conclude that SSRIs can cause weight change in the form of decrease of body weight. This property of SSRIs can be used clinically by prescribing these drugs to obese psychiatric patient without any fear of withdrawal of drug."



Wow. Seriously? Of course, it's an abstract, and as a result, many details are not included. But still, the conclusions seem unethical to me.


Here's the abstract:





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