[La...] Posted February 20, 2017 Share Posted February 20, 2017 "GABAergic neurons are located in spinal nociceptive circuits suggesting that drugs with affinity at these receptors, including benzodiazepine-like drugs, may provide an alternative to opioids for the treatment of pain. However, systemically administered conventional benzodiazepines fail to produce antihyperalgesic effects, likely due to their concurrent sedative properties." https://www.ncbi.nlm.nih.gov/pubmed/28176641 Link to comment Share on other sites More sharing options...
[Te...] Posted February 20, 2017 Share Posted February 20, 2017 It sounds as if they want to develop another benzo, this time for hyperalgesia and circumventing the sedative properties. No mention of people having dependent issues or problems with benzos as well as opoids. What do you think? Link to comment Share on other sites More sharing options...
[La...] Posted February 20, 2017 Author Share Posted February 20, 2017 Yes, I think you're right, Terry. I will not be holding my breath to see if they can figure out a benzo-like pain medication that doesn't cause sedation. Even if they do create such a beast, it will likely cause physical dependency, so that would be enough of a downside for many people. Link to comment Share on other sites More sharing options...
[Te...] Posted February 21, 2017 Share Posted February 21, 2017 Exactly, Lapis! That's what I think. Link to comment Share on other sites More sharing options...
[li...] Posted February 25, 2017 Share Posted February 25, 2017 Clonazepam can be effective - up to a point ... Link to comment Share on other sites More sharing options...
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