4 month setback from oxycodone

[[ti...]]

Hey everyone, 

I'm 3.5 years off benzos and had been doing ok for the most part. I'd say I was 80% better as long as I avoided triggers and even if I stumbled on a trigger, the wave would only last anywhere from a few days to a week or two. 4 months ago I took 10 mg of oxycodone for pain from passing a kidney stone. A day later I got thrown back into a huge wave, mostly nerve pain symptoms. It's been on and off since then but mostly on. I don't really understand why this setback is lasting so long and I'm scared. Opioids don't affect gaba or gaba receptors, right? I tried to drink a beer at 1 year off and had less of a setback than this, and alcohol actually affects gaba receptors. I don't understand any of this. I'm in agony.

[[je...]]

Hi @[ti...]

Welcome to BenzoBuddies!

I'm so sorry to hear you're experiencing a setback. It's understandable that you're scared. As you probably know, people have different reactions to different meds. I know you say it comes in waves, but have noticed during the times when it does occur whether there are any slight improvements and if the duration is getting a bit shorter? Are you keeping a journal of the intensity and the times? Sometimes improvement is so gradual that we don't notice it. 

I am sorry you have to go through all this again when you have been recovering so well.

[[ti...]]

No, if anything it's gotten worse over the 4 months. The last 3 weeks have been hell.

[[Na...]]

I think we're in such a fragile situation that almost anything might create a setback. 

But, setbacks overwhelmingly tend to be transitory. Even if they can take a long time to reverse. Of course, when you're suffering every moment seems like eternity.

[[Ma...]]

@[ti...] I so understand your predicament. Almost 3.5 years out and I’ve been feeling awful again since getting Covid 3 months ago. I’m reacting to everything again after feeling almost healed. The internal anxiety is debilitating right now - something I haven’t felt in years since my taper. Are you having any improvements?

[[ti...]]

On 14/02/2024 at 14:09, [[N...] said:

I think we're in such a fragile situation that almost anything might create a setback. 

But, setbacks overwhelmingly tend to be transitory. Even if they can take a long time to reverse. Of course, when you're suffering every moment seems like eternity.

I really hope so. 

7 hours ago, [[M...] said:

@[ti...] I so understand your predicament. Almost 3.5 years out and I’ve been feeling awful again since getting Covid 3 months ago. I’m reacting to everything again after feeling almost healed. The internal anxiety is debilitating right now - something I haven’t felt in years since my taper. Are you having any improvements?

Not yet. I thought I was through the worst of withdrawl and now this setback has me questioning if I'll ever get back to my old baseline. 

[[Ti...]]

Yes, opioids have an inhibitory effect on gabaA, which is why many people on opioids long term for chronic pain are also put on benzos and other psychotropics.

 https://medicalxpress.com/news/2020-06-reveal-neural-mechanisms-underlying-opioid.html
 

I had to take opioids for a ruptured appendicitis early in 2022 and it didn’t throw me into a wave, but other drugs have. Actually I got a little relief from benzo WD pain while healing from that surgery and sepsis.
 

Hopefully your setback will be short lived for you and you get back to your baseline soon. 

[[ti...]]

On 23/02/2024 at 14:57, [[T...] said:

Yes, opioids have an inhibitory effect on gabaA, which is why many people on opioids long term for chronic pain are also put on benzos and other psychotropics.

 https://medicalxpress.com/news/2020-06-reveal-neural-mechanisms-underlying-opioid.html
 

I had to take opioids for a ruptured appendicitis early in 2022 and it didn’t throw me into a wave, but other drugs have. Actually I got a little relief from benzo WD pain while healing from that surgery and sepsis.
 

Hopefully your setback will be short lived for you and you get back to your baseline soon. 

I read that about the gaba effect, but a 4 month set back from a one time dose of opioids seems crazy.