[De...] Posted May 5 Share Posted May 5 Riluzole and Sorafenib in patients with advanced solid tumors: a Phase I trial https://scienmag.com/riluzole-and-sorafenib-in-patients-with-advanced-solid-tumors-a-phase-i-trial/ " Overexpression of metabotropic glutamate receptor 1 (GRM1) has been implicated in the pathogenesis of multiple cancers. Riluzole, an inhibitor of glutamate release, showed synergistic antitumor activity in combination with the multi-kinase inhibitor sorafenib in preclinical models." Quote Link to comment Share on other sites More sharing options...
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