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@KNACKERED

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Knackered Mixes It Up with Benzos


[kn...]

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Knackered Mixes it Up with Benzos

   Hey there, Knackered here.  I learned early in my college life that you should never consume the party punch containing a mixture of different alcoholic beverages and god knows what else.  If you’ve experienced trying to budget while you own credit cards, you know what a mess that can make of your finances.  Unless they’re together from early days, cats and dogs don’t get along well.  And unless you’ve got a very strong constitution, you don’t mix having diarrhea with being stuck on an elevator.  Much better to take the stairs up to the restroom.

   I would also imagine that all of us around here have experienced the good, and more than likely, the bad of mixing other drugs while on a Benzo taper.

I’ve tried several times now, and the results have always left me in enemy territory for at least a week or so.

   I’d also like to think that by the time someone my age has gone through this that they’d be smart enough not to repeat it.  Nevertheless, I agreed with my provider at my most recent appointment that I should add some Pregabalin (Lyrica) to take ‘the edge’ off my Benzo taper symptoms.  We (I) tried it at a very low dose, but found myself in tolerance after just a few days.  Somewhere along the line, I agreed to try again by doubling the dose as it was partially effective the first time around.  That was mid day yesterday.

  Last night, I found myself down the rabbit hole with ‘Alice when she’s ten feet tall…” (Jefferson Airplane-White Rabbit -June, 1967).  During the night, I found myself in broad daylight out in front of the house, mowing and edging the lawn.  Knowing that I had to get back to bed because we had arranged to have some home repair folks coming early, I left the back door unlocked.  Sometime later I heard the repair crew inside the house, talking and checking out something in the basement.  I realized that I had to get up again, but could not lift the bedding.  I called to my son, age circa 5 or 6 (but now actually 46) and he came to assist me.

   Sometime later, I heard the dog barking from the distance.  I asked my wife to please get up and do the deed, as I felt paralyzed.  Upon waking, I discovered that the dog had been fed, let out and brought back in (by me??).

   I should, at this point, emphasize that I don’t do recreational drugs, but remember:  “And if you go chasing rabbits; And you know you’re going to fall;  Tell ‘em a hookah smoking caterpillar;  Has given you the call;  He called Alice;  When she was just small.”

   I didn’t leave the bed until lunch time today.  Checking into the internet med interaction website, apparently there is only a ‘moderate’ chance of harmful interaction with Lyrica and Benzos.  But remember: “One pill makes you larger and one pill makes you small.  And you might find Alice “When she’s ten feet tall”.

   

 

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[Li...]

Posted

Oh my, @[kn...].

Interactions with other drugs are not the only thing to be concerned about with Lyrica / pregabalin. Per its FDA drug label, the following serious adverse reactions have been reported:

 

  • Angioedema
  • Hypersensitivity
  • Suicidal Behavior and Ideation
  • Respiratory Depression
  • Dizziness and Somnolence 
  • Ophthalmological Effects
  • Creatine Kinase Elevations
  • PR Interval Prolongation
  • Decreased Platelet Count 
  • Peripheral Edema
  • Increased Risk of Adverse Reactions with Abrupt or Rapid Discontinuation

It sounds like you experienced at least dizziness and somnolence and perhaps respiratory depression as well.  I hope you’re feeling ok now.

 

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[kn...]

Posted

I had looked at the side effects initially when my NP first suggested 25 mg (lowest possible dose) and I was skeptical, but went ahead and tried  it at that level for several days. It helped a lot but I found myself in tolerance within about 5 days time.  NP prescribed 50mg @ the next appt.  I picked it up around noon and took the one time 50 mg dose. My blog describes what happened that night.  Ok now, but it took a good 24 hrs to get that way. Who woulda thought???  Thanks for weighing in on this. 

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