Use of LDN

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Off Ativan since November and still feel pretty awful most of the time, though some days able to be active. I have POTS (postural orthostatic tachycardia syndrome) and joined a group for that. I've learned some of my symptoms I thought were benzo related might be POTS and that Ativan can help with POTS flares. Now I'm wondering if it was POTS or withdrawal.

 

Anyway, I was going to try low-dose naltrexone for the POTS and a pain condition. Took it for a few days at night, then switched to AM, but felt so bad I ended up in urgent care. I had been feeling bad anyway. I got a bag of IV fluids, barely made it home, but then the awful feeling lifted and I got more sleep that night than in a long time.

 

I quit taking it having found a site that warns it can exacerbate withdrawal (along with other things from magnesium to chamomille).  I found an old thread here that someone felt it helped their mood. I badly want to try it again for the POTS and pain but concerned re worsening if symptoms are still WD and not POTS (why do they all have to cross over so frequently?)

 

Anyone here taking LDN for/during withdrawal or for any other conditions have any input?

 

This is from that site:  LDN or LOW-DOSE NALTREXONE: Naltrexone and its active metabolite 6-β-naltrexol are competitive antagonists at μ-opioid and κ-opioid receptors, and to a lesser extent at δ-opioid receptors. Standard therapeutic doses of naltrexone blocks these receptors, which does two things; it prevents inhibition of GABA receptors (normally, signaling through the GABA receptors inhibits the activity of neurons; many drugs inhibit GABA and thus “free up” neuronal activation; preventing inhibition of GABA allows GABA’s normal inhibition activity to take place) and it blocks dopamine release.