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Antidepressant advice

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I have been on antidepressants since 1999 along with benzos. I have taken Zoloft, effexor, paxil and am currently on lexapro. My diagnoses are panic disorder, major recurrent depression, and PTSD. I am seeing a new psychiatrist and she wants me to try prozac. I am wondering if anyone has had success treating depression/anxiety with an antidepressant?
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