Why half life isn't everything (clonazepam)

[[li...]]

https://books.google.nl/books?id=FWkw__AtD3EC&pg=PA49&lpg=PA49&dq=clonazepam+absorption+intestine&source=bl&ots=MQD2shaojJ&sig=PDUXXAImwU4eJOAKCubRn6HHG8I&hl=nl&sa=X&ved=0ahUKEwjI1YemgI7SAhXGVxoKHTUTA4o4ChDoAQg6MAQ#v=onepage&q=clonazepam%20absorption%20intestine&f=false

 

'distribution phase concentrations that are 10 times predose concentrations'

As you all know, clonazepam has a long duration of action.

 

I hope the google book thing works.

[[Te...]]

No, I didn't get it.

[[xe...]]

sure -- but how is this really relevant to the withdrawal process? Like, it's intellectually interesting, but I'm not sure how it would inform a withdrawal strategy.

 

Benzo withdrawal is dead simple, and extremely, extremely difficult. But you just do it, either directly or with a crossover, slowly enough to not go into seizures. You tolerate the intolerable until it becomes tolerable again, and then you're through it, at at some point life starts to make sense again.

 

I don't believe that you can out think it, or that an intimate understanding of the neurochemistry is actually that helpful. You just do it one day at a time until you don't have to do it anymore.

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Terry, maybe trying again works. A moment ago it didn't work for me, then I tried again and it did work ...

 

So just CT then ?

 

I mean, you can't always taper clonazepam and diazepam isn't always the answer.

Sometimes it's a lot, lot more complicated.

 

My situation already is intolerable. Sometimes things are more complicated than they seem.

 

In my situation, doctors managed to push me ' ahead' a few years, and now I'm at a point where I can't do a normal taper. I wish I had done a CT in 2012 or 2013.

 

Xerxes, you probably haven't been on clonazepam (for long) ? For me, it's absolutely not a calming or sleeping tablet. From what I get from people on this website, clonazepam (when used long term) really is the hardest (intensity/duration) of all benzos. It's the worst. And I got the second worst with lorazepam (signature).

 

Anyway, this is the chewing the fat section and the post wasn't really a tapering question ...

[[xe...]]

Xerxes, you probably haven't been on clonazepam (for long) ?

 

yeah, was my second benzo, I took ~2mg for the better part of a decade in the late 90s / 00s. Direct tapering was impossible, crossover was brutal.

 

would still probably be my first choice if I ever had to reinstate, for a number of reasons. Relatively "clean burning", all things considered. I think it's properties make it a decent bet if long-term use is actually required, but definitely a double-edged sword because the same things make it rather miserable to withdraw from -- though I thought phenazepam was worse.

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