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Accidentally back on benzos/Zdrugs plus remeron - extreme insomnia/anxiety, need plan to getoff both


[Al...]

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I'm having a bad problem right now involving Ambien, Remeron, Xanax, Benadryl, Anxiety, Insomnia, GI problems, and fibromyalgia.

 

I have a history of ambien use. 2 years ago I used 5-10MG of Ambien every night for 9 months. I started gradually having mild anxiety and depression throughout the 9 months so I decided to quit and then I did a 3 months taper. It was probably too fast because I had terrible anxiety throughout the process and it never stopped after I jumped. I was clean for 4 months.

 

Then 5 months ago I had an incident which has since plunged my life down the toilet bowl and I have been terribly ill ever since, lost 30 pounds, and my anxiety and panic disorder has transformed into full blown agoraphobia. It started when I took an antibiotic for an ear infection. I had an allergic reaction and I had to start taking 50-75 mg of Benadryl every night. The next day I started a 5 day course of a different antibioitic, took corticosteroids, and took 0.25mg xanax to get to sleep.

 

All was fine until 3 days later when I suddenly got chest/back pain, gastric burning, and a panic attack. This started a 5 month cascade of gradually elevating anxiety and gastric symtoms which was misdiagnosed as GERD. I went on many medications including prilosec, zantac, benadryl, antacids, tylenol, an experiment with librax (about 8 pills), and a few doses of muscle relaxer.

 

I was on a cycle of using Xanax every 3 days and Benadryl every night. Every 3 days I would have a panic attack and take 0.25mg of Xanax, which has an interaction with Prilosec so it was probably actually more like 0.5mg. The gastric symptoms would strangely improve whenever I took the Xanax and then deteriorate over the next 3 days until it was time for the next Xanax. My nightly dose of 25mg-75mg Beandryl also helped and I would typically be better in the beginning of the day and then deteriorate throughout the night until it was time for the next Benadryl. At the time I thought Benadryl was just an antihistamine and did not know that it was also an anticholinergic and a mild SSRI.

 

3 months ago the gastric symptoms went into a constant steady state with no remissions and I started having wierd muscle twitching and electric sensations. So I went on a witchhunt to remove all of my medications in suspicion that one of them was causing my GI symptoms, which had eluded my GI doctor and all of his tests. First I got rid of the prilosec, zantac, antiacids. This didnt help. Then I tried to get off the Benadryl and that's when the shit hit the fan.

 

Muscle stiffness and Insomnia from trying to quit Benadryl drew me back to Ambien. It started with 1mg doses and then quickly went to 2 and then 5 in a matter of days. The first day off Benadryl I had terrible anxiety and I was immediately in a state of having extreme insomnia and after a couple nights of taking Ambien or missing sleep I also had fibromyalgia, which further prevented me from sleeping as I could not find a comfortable position to sleep in. I've never had fibromyalgia in my life. For the next 2 weeks I would flop between different combinations of Benadryl and Ambien as my condition continued to deteriorate. I was averaging 2 or 3 hours of sleep per night.

 

2 weeks ago I saw a psychiatrist sleep doctor who Prescribed Remeron 7.5mg. I started by cutting it to 3.75mg which worked wonderfully for the first 5 days. I didnt need any Ambien and was getting 9 hours of sleep. However, I had side effects like dry mouth, dehydration, weakness, exercise intolernce, anxiety, suicidal ideation, memory issues, binge eating on junk, and daytime tiredness. Then on the 6th day I was having muscle stiffness, muscle spasms/twitches, and insomnia. I could not sleep on 3.75mg. After a drink (i dont normally drink), a hit of weed (i dont normally smoke), and then another 3.75mg to bring it up to 7.5mg, I STILL could not sleep. I could not sleep until I added 2.5mg of Ambien, and then I slept for 3 hours. This situation might have been amplified by having a steroid trigger point shot and a sedated procedure 2 days prior.

 

Nevertheless, it scared me away from Remeron. I was scared of the side effects, the dose escalation, and possibly Neuroleptic Malignant Syndrome. I also quit Claratin 10mg, which I'd be taking for years while going on an antihistamine witchhunt and suspected I had 'Histaminosis'. For the next 4 days I would use Ambien 2mg and then 5mg and then two nights at 10mg, and I was still only getting 3-5 hours of sleep. I was hoping my GI symptoms would go away, if I was on just Ambien for a while. They didnt. Soem of the twitching was still there too. My psychiatrist told me to go up to 12.5mg of Ambien CR. Hell no. I was already possibly getting addicted to Ambien and didnt want to cement that with a long course of high doses and cement this addiction after everything I went through over the past 2 years.

 

Over the last 2 nights I did an experiment where I 'reinstated' Remeron at 1mg and used 1mg of Ambien. One to initiate sleep and one to maintain sleep, instead of using an unnecessarily large dose of a long acting drug to initiate sleep or an unneccessarily large dose of a short acting drug to maintain sleep. Miraculously it worked. On only 1mg of remeron and 1mg of Ambien I have gotten 9 and 10 hours of sleep during the previous 2 nights. However, today I am again having some issues with minor twitching and electric sensations throughout my body, which I woke up with, and after thinking of it too long I am having bad anxiety.

 

I don't know whether I am having a withdrawal from Ambien, a withdrawal from Remeron, side effects of Remeron, a withdrawal from one of the previous drugs (I havent had Xanax in 2 weeks), etc. After having only about 10 or 15 doses of Ambien at an average of 3-4mg per night, am I already addicted? Am I KINDLED? Do I need to taper Ambien in order to avoid seizures or brain damage, regardless of Remeron? For how long - a week, a month, months? Am I having some rare side effect syndrome of Remeron and need to go back on just ambien? Do I need to taper the tiny dose of remeron I took for a week? Do I need to go back on Benadryl or Xanax? Did I get addicted to the Xanax every 3 days?

 

I feel like I urgently need a professional to work all of this out and tell me which doses of what I need to take over what time frame in order to avoid harm or seizures and assure me that I'm not having Neuroleptic Malignant Syndrome or something like that. I want my life back. I know these all look like tiny doses and time frames to you guys but I feel like I'm going insane, or I'm going to die.

 

What do you guys think?

 

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Glad you're here, AlienResources.  We're a community of non-professionals who share personal experiences with medications.  It will be difficult for anyone to do more than speculate what might be going on, but here are a couple of pertinent links to start posting to the wider membership:

 

General Taper Plans 

Withdrawal Support 

 

Many of our members are not able to read large chunks of text.  You may want to decide what can be left out of your introduction narrative to post to the wider community so that you'll get more feedback.  I would stick mainly to the benzodiazepine and z-drug history, though it would also be helpful to know which antibiotic was prescribed at first.  Quinolone antibiotics can cause issues when combined with benzodiazepine use, so that is a potential factor in your symptoms.

 

Please take some time to Create a Signature. This will help other members understand your history so they will be better able to support you.

Go to the top of the page and select Profile, then choose Forum Profile, insert drug history/timelines into the text box and click Change Profile.

 

When you have a chance, I highly recommend that you take a look at The Ashton Manual, which is an authoritative source on what to expect during withdrawal and recovery, authored by Dr. C. Heather Ashton, who is an expert in the field. It provides a great deal of information that can be very reassuring during any stage of this process, including a list of common symptoms with helpful explanations on the reasons for their existence.

 

Best of luck to you,

Challis

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