Why Does Remeron Stop Working?

[[al...]]

Why does Remeron stop working for sleep so quickly , at least with me? Initially, I was prescribed 15 mg. On the first day I slept 8 hours. I was shocked. Hadn't slept since the 8th of May. Then the second day I was back to 2-3 hours. This went on for 2 months until the doc took me off it (or tried to, I knew better). So I tied the 7.5 mg and same thing on the first night. But this time I was able to sleep for 2 nights in a row and then 2-3 hours on the third night. Now it's also not working again.

Help, please?

 

I have to take 1.9mgK at night which I'm tapering.

[[bu...]]

I took 22.5-30 mg/day for almost 3 years, and did not have any loss of efficacy.  Even after I stopped daily dosing, I occasionally took a very small dose (3.75-7.5mg) for sleep, and it worked very well.

[[al...]]

I'm on 7.5 with no results. Should I keep lowering it to 3.5 and see if that works?

[[Ka...]]

I have been on remeron for 4 weeks. The first 16 days I slept great but as I went down in my taper it didn't work as well. My doctor had me increase the dose to see if that would help and it worked well 2 days but other days I struggle. I think it's the benzo not the remeron. If I was off the benzo, I know the mirtazipine would help me better with sleep. It has helped with appetite and anxiety and I am so thankful for this med. I'd be so sick without it.

[[al...]]

I think it's the benzo not the remeron.

 

That's what worries me. If it is the benzo and I haven't even really begun a proper taper, nothing will aid in sleep.

[[Ka...]]

Maybe with the mirtazipine, you could taper faster. The mirtazipine really helps with GI troubles and anxiety.

 

Also talk to your doctor. There is something else out there you can take along with the mirtazipine for sleep. Have you tried a Unisom with it?

[[al...]]

Maybe with the mirtazipine, you could taper faster. The mirtazipine really helps with GI troubles and anxiety.

 

Also talk to your doctor. There is something else out there you can take along with the mirtazipine for sleep. Have you tried a Unisom with it?

 

Haven't tried that. My issue is not sleep onset but maintenance, just to elaborate.

[[al...]]

Maybe with the mirtazipine, you could taper faster. The mirtazipine really helps with GI troubles and anxiety.

 

Also talk to your doctor. There is something else out there you can take along with the mirtazipine for sleep. Have you tried a Unisom with it?

 

The Remeron really does help me with nausea, GI issues, and appetite. I was an ambulating toothpick prior to the Rem. However, once the doc sees that I've gained weight, eating well, and have no complaints of nausea or stomach pains, they automatically assume I'm 'healthy' again and that it has to be a psychological condition (never the benzos!).

[[Ka...]]

I took my 22.5 mg of remeron with a half of a unisom and slept all night last night! 9.5 hours. I always do better with sleep in the second half of my week as I taper on Mondays.

 

I really hope your doctor helps you out with this sleep issue. I know how hard it is to want to sleep and you can't. Benzos are evil to our bodies.

[[Ra...]]

I use to take 15mg of remeron it worked well at first. Several months later it lost it's effectiveness so the dosage was increased to 30mg and I can now sleep again. The reason the drug stops working is because your body becomes tolerant to it. Have you tried perhaps taking a larger dose? I am so glad I did and was able to sleep. If I listened to the internet I would have ended up probably stopping the drug due to ineffectiveness, thank God I did not.

[[al...]]

I use to take 15mg of remeron it worked well at first. Several months later it lost it's effectiveness so the dosage was increased to 30mg and I can now sleep again. The reason the drug stops working is because your body becomes tolerant to it. Have you tried perhaps taking a larger dose? I am so glad I did and was able to sleep. If I listened to the internet I would have ended up probably stopping the drug due to ineffectiveness, thank God I did not.

 

Yes, I know, the net will always claim that Rem is most sedating at lower doses because of the receptors and AD effect. 

 

 

[[al...]]

I use to take 15mg of remeron it worked well at first. Several months later it lost it's effectiveness so the dosage was increased to 30mg and I can now sleep again. The reason the drug stops working is because your body becomes tolerant to it. Have you tried perhaps taking a larger dose? I am so glad I did and was able to sleep. If I listened to the internet I would have ended up probably stopping the drug due to ineffectiveness, thank God I did not.

 

If that's true, my body became tolerant to 15 mg the second day. :/

[[Ra...]]

Are you certain? On the day it stopped working did you notice a difference in your diet or exercise? Were you excessively stressed? I really doubt it would lose it's effectiveness that quickly. Something else must have been going on.

[[al...]]

Are you certain? On the day it stopped working did you notice a difference in your diet or exercise? Were you excessively stressed? I really doubt it would lose it's effectiveness that quickly. Something else must have been going on.

This is what happened. I visit the sleep 'specialist' on the 2nd of July after not being able to sleep since the 8th of May. He says that my chronic insomnia is secondary and most likely due to a mood disorder. He thinks it's depression and hands me some Remeron after telling him I don't respond well to most SSRIs and am already on 2 mg K. So I go home and take the 15 mg that night. Following morning: UNBELIEVABLE! Miraculous pill gives me 8 hours non-stop sleep and I wake up refreshed! I throw a proverbial party throughout the day. Next night: I wake up after two hours sleep : /. Then I go back to see doc about two weeks ago and he says he can't do anything for me and I should see a shrink. I explain about benzo tolerance and he nods, tilts his head and exclaims, "that's an interesting theory". So that's what's happened. Sometimes I'd get 2 hours, sometimes I was REALLY lucky and got 3.5. But during the process, I've lost all sanity.

 

I go for a 30 min walk at 6-7PM. Nothing strenuous.  Throughout the day, I do crunches and silly leg exercises. I do stretches. I used to meditate but dismissed it out of spite. I'm a pescatarian (no animal protein aside from wild-caught salmon). Don't drink, don't smoke. Don't sleep.

 

[[al...]]

I'm still giving it a go now at 7.5 mg because it's alleviated my GI symptoms and appetite is hearty. I'd be off it if my nausea wouldn't come back, along with the awful stomach pains. Do I need an endoscopy at 36?

[[Ra...]]

There are probably other factors you may have missed alizarin, for example where do you live? In a busy city? The time of the week may determine how many cars/trains pass by your house and the noise of the engines differ... Are you making sure to go to the bathroom before you go to bed? Are you eating a snack before bed? Are you making sure there are no lights on at all? Limiting computer use at night times? I find it hard to believe that your sleeping pattern is entirely based on luck.

[[al...]]

There are probably other factors you may have missed alizarin, for example where do you live? In a busy city? The time of the week may determine how many cars/trains pass by your house and the noise of the engines differ... Are you making sure to go to the bathroom before you go to bed? Are you eating a snack before bed? Are you making sure there are no lights on at all? Limiting computer use at night times? I find it hard to believe that your sleeping pattern is entirely based on luck.

 

Well, I don't have a snack before bed. I eat at about 8 and then go to sleep around midnight. I do use the computer, but heck, before the 8th of May, I'd fall asleep with it next to me. Things just changed spontaneously.

[[Ra...]]

I still find it hard to believe. Your body built up tolerance EXTREMELY quickly if what you say is true. I suppose you could always try something else for sleep...

[[al...]]

Yes, it makes no sense. Just like developing tolerance to an extra 1 mg K during hospitalization in May. Before that, I had been on 1 mg K for ten years and sleep like a log.

 

Dont think I'll be able to taper if I have to start off this way.